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Title: |
Advances in Drug Resistance Research |
Search Result:
| Edited by: |
Christudas Morais |
| ISBN10-13: |
1631171313 : 9781631171314 |
| Format: |
Hardback |
| Size: |
230x155mm |
| Pages: |
220 |
| Weight: |
.520 Kg. |
| Published: |
Nova Science Publishers, Inc (US) - March 2014 |
| List Price: |
194.99 Pounds Sterling |
| Availability: |
In Stock
Qty Available: 2 |
| Subjects: |
Public health & preventive medicine |
| Drug resistance continues to be a major problem in the effective treatment of many diseases. Resistance to chemotherapy, whether intrinsic or extrinsic, is the result of at least three well defined mechanisms: prevention of the interaction of drug with the target, decreased intracellular concentration of the drug due to an increased efflux or a decreased influx, and enzymatic modification or destruction of the drug. With the advancement in technology, the molecular mechanisms of drug resistance have been unravelling at a rapid rate. This book is a timely review of such advances in drug resistance research. The nine chapters of this book, written by a group of clinicians and scientists, elegantly summarises recent advances in our understanding of this important clinical problem with emphasis on cisplatin, fibroblasts, natural compounds, erythropoiesis-stimulating agents, prostate cancer and kidney cancer. This book will be an important contribution to science, and an invaluable tool for researchers who are interested in drug resistance. |
| Table of Contents: |
| Mechanisms of Cisplatin Resistance: DNA Repair & Cellular Implications; Multi-Drug Resistance in Cancer & New Approaches for its Overcoming; Tumor Fibroblasts: Pivotal Players in Drug Resistance; Erythropoiesis Stimulating Agent Resistance; Therapeutic Options for Metastatic Castration Resistant Prostate Cancer: Has the Situation Improved?; Current Trends in Prostate Cancer Treatment & Drug Resistance; Resistance of Metastatic Renal Cell Carcinomas to Chemo & Immunotherapy: Clinicians’ Perspective; Resistance of Renal Cell Carcinoma to Targeted Therapy; Molecular Mechanisms of Sunitinib Resistance in Renal Cell Carcinoma.
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