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Title: Stem Cells
Sub-title: Cellular & Drug Therapies -- Volume 2
By (author): Philippe Taupin
ISBN10-13: 1629487783 : 9781629487786
Format: Hardback
Size: 260x180mm
Pages: 360
Weight: .568 Kg.
Published: Nova Science Publishers, Inc (US) - March   2014
List Price: 194.99 Pounds Sterling
Availability: In Stock   Qty Available: 1
Subjects: Medical research
Stem cells are the building blocks of the body. They can develop into any of the cells that make up our bodies. Stem cells carry a lot of hope for the treatment of a broad range of diseases and injuries, spanning from cancers, diabetes, genetic diseases, graft-versus-host disease, eye, heart and liver diseases, inflammatory and auto-immune disorders, to neurological diseases and injuries, particularly neurodegenerative diseases, like Alzheimer's and Parkinson's diseases, cerebral strokes, and traumatic brain and spinal cord injuries. Stem cell research is therefore as important for our understanding the physio- and pathology of the body, as for development and therapy, including for the nervous system. This book aims at providing an overview and in depth analysis of recent developments in stem cell research and therapy. It is composed of recently published review articles that went through a peer-review process.
Table of Contents:
Introduction; Adult Neurogenesis in Etiology & Pathogenesis of Alzheimer’s Disease; Adult Neurogenesis & Aneuploidy in Etiology, Pathogenesis & Pathology of Alzheimer’s Disease; Adult Neurogenesis, Neural Stem Cells & Alzheimer’s Disease: Developments, Limitations, Problems & Promises; Oxidative Stress in Adult Neurogenesis & in the Pathogenesis of Alzheimer's Disease; Adult Neurogenesis, Neuroinflamation, & Therapeutic Potential of Adult Neural Stem Cells; Adult Neurogenesis & Drug Therapy; Neurogenesis & the Effect of Antidepressants; Neurogenic Drugs & Compounds to Treat CNS Diseases & Disorders; Patent Evaluation. Thirteen Compounds Promoting Oligodendrocyte Progenitor Cell Differentiation & Remyelination for Treating Multiple Sclerosis: Wo2010054307; Patent Evaluation. Antibodies against CD20 (Rituximab) for Treating Multiple Sclerosis: US20100233121; Umbilical Cord Blood & Alpha-3 Fucosyl Transferase-Treated Haematopoietic Stem Cells for Transplantation; Patent Evaluation. Cell Lines Expressing Mutant FX Proteins to Generate Proteins with Reduced Rate of Fucosylation: Wo2010/141478; Patent Evaluation. Modulation of GDP-Fucose Level for Generating Proteins with Reduced Rate of Fucosylation (Wo2010141855); Patent Evaluation. Chimeric Proteins Comprising the Constant Region of Immunoglobulins for Treating Haemophilia B (WO2005001025); Patent Evaluation Parthenogenetically Activated Human Oocytes & Parthenogenetic Embryonic Stem Cells: US20100233143; Tuberous Sclerosis Complex: A Paradigm for Studying Adult Neurogenesis & Brain Tumors; Adult Neurogenesis in Alzheimer’s Disease & Therapies; Indacaterol for the Treatment of Patients with Moderate-to-Severe COPD; Conclusions; Index.
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