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Title: |
Regucalcin |
| Sub-title: |
Genomics, Cell Regulation & Disease |
Search Result:
| Edited by: |
Masayoshi Yamaguchi |
| ISBN10-13: |
1621002594 : 9781621002598 |
| Format: |
Hardback |
| Size: |
155x230mm |
| Pages: |
157 |
| Weight: |
.476 Kg. |
| Published: |
Nova Science Publishers, Inc (US) - January 2012 |
| List Price: |
199.99 Pounds Sterling |
| Availability: |
In Stock
Qty Available: 1 |
| Subjects: |
Proteins |
| Regucalcin is a protein which is highly differentiated due to increased conservation of the regucalcin genes throughout evolution in vertebrates. Regucalcin plays a multifunctional role in cellular regulation, including an inhibitory role in protein kinases, protein phosphatases, NO synthase, nuclear DNA and RNA synthesis. Regucalcin suppresses an enhancement of cell proliferation and apoptotic cell death that are induced by various signalling factors. Regucalcin plays a pathophysiological role in many metabolic disorders in humans. This book introduces recent topics of regucalcin studies concerning the genomics, cell regulation and diseases associated with this protein. |
| Table of Contents: |
| Preface; Structure of regucalcin gene; Transcriptional regulation of regucalcin gene expression; Hormonal regulation of regucalcin gene expression; Change in regucalcin gene expression in patho-physiological state; Role of regucalcin in intracellular calcium homeostasis; Reversible effect of regucalcin on calcium effect in enzyme regulation; Role of regucalcin in the regulation of nuclear signaling; Role of regucalcin in protein synthesis & degradation; Suppressive role of regucalcin in apoptosis |
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