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Title: Actin
Sub-title: Structure, Functions & Disease
Edited by: Victoria A Consuelas, Daniel J Minas
ISBN10-13: 1621001911 : 9781621001911
Format: Hardback
Size: 260x180mm
Pages: 296
Weight: .732 Kg.
Published: Nova Science Publishers, Inc (US) - March   2012
List Price: 247.99 Pounds Sterling
Availability: In Stock   Qty Available: 1
Subjects: Proteins
Actin is a globular protein found in all eukaryotic cells and plays a central role in cell morphology, cell adhesions, cell contractility and motility, signal transduction, transcription and its regulation, cytokinesis and synapse formation, as well as malfunctioning of actin which can lead to various diseases. This book presents topical research in the study of the structure, functions and diseases related to actin. Topics discussed include actin dynamics and remodelling of cell-cell junctions in epithelial morphogenesis; osmotic pressure and the polymeric forms of actin; the molecular mechanisms of actin regulatory proteins and actin cytoskeleton alterations.
Table of Contents:
Actin Dynamics & Remodeling of Cell-Cell Junctions in Epithelial Morphogenesis; Actin: Structure, Function & Disease; Osmotic Pressure: A Tool to Investigate the Polymeric Forms of Actin; Two Communication Bridges to One Versatile Molecule; Stressed Out & Actin Up: Stress-Activated Protein Kinase Regulation of Actin Remodeling Directs Endothelial Cell Morphology & Migration; The Molecular Mechanisms of Actin Regulatory Proteins; Actin Cytoskeleton Alterations: Are There any Consequences?; Role of the Actin Cytoskeleton in Tumor Escape to Immune System & Acquisition of Tumor Resistance to Cytotoxic Treatment; Insight into Force Transmission Along Actin Filaments: Sliding Movement of Actin Filaments Containing Inactive Components on Myosin Molecules; Hypoxia Induces Endothelial Barrier Dysfunctions in Lungs: Nitric Oxide Perturbs Actin Dynamics in Endothelial Cells.
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