|
Title: |
Structural Biology of Antiapoptotic Proteins of BCL-2 Family |
Search Result:
| By (author): |
Valery G Veresov |
| ISBN10-13: |
1619423944 : 9781619423947 |
| Format: |
Hardback |
| Size: |
260x180mm |
| Pages: |
257 |
| Weight: |
.632 Kg. |
| Published: |
Nova Science Publishers, Inc (US) - January 2013 |
| List Price: |
203.99 Pounds Sterling |
| Availability: |
In Stock
Qty Available: 2 |
| Subjects: |
Biochemistry |
| The BCL-2 family proteins are crucial regulators of the apoptotic process. This book covers recent structure-based insights into the mechanisms of action of antiapoptotic BCL-2 family proteins as well as into the interactions between antiapoptotic proteins and their ligands. While the main focus is on the apoptotic processes in mammals, the great part of the book is devoted to viral homologues of Bcl-2 family antiapoptotic proteins. |
| Table of Contents: |
| Preface; Introduction; Proteins of BCL-2 Family; Extrinsic & Intrinsic Pathways of Programmed Cell Death; Models of Apoptosis; Antiapoptotic Proteins. Basic Properties & Functions; Gene Products & Tissue Specificity of Expression of Antiapoptotic Proteins; Structures of Antiapoptotic Proteins in Solution; 3-D Structures of Viral Antiapoptotic Proteins in Solution; What Can We Know & What Can We Anticipate About the Structures of Antiapoptotic Proteins at Membranes; Regulation of Antiapoptotic Proteins; The Endoplasmic Reticulum in Apoptosis & Antiapoptosis; The Antiapoptotic Action of Antiapoptotic Proteins; Physiological Role of Antiapoptotic Proteins; Carcinogenesis, Aberrant Apoptosis & the Proteins of BCL-2 Family; Therapeutic Strategies Against Antiapoptosis for Cancer Treatment; Conclusion. |
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