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Title: Regulation of Vitamin A Homeostasis by the Stellate Cell (Vitamin A-Storing Cell) System
By (author): Haruki Senoo, Kiwamu Yoshikawa, Yoshihiro Mezaki, Mayako Morii, Mutsunori Fujiwara
ISBN10-13: 1617613134 : 9781617613135
Format: Paperback
Size: 140x215mm
Pages: 55
Weight: .108 Kg.
Published: Nova Science Publishers, Inc (US) - February   2011
List Price: 52.99 Pounds Sterling
Availability: Temporarily Out of Stock, more expected soon 
Subjects: Dietetics & nutrition
Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis. In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesise a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins. Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts. This book discusses and presents research on vitamin A-storing cells.
Table of Contents:
Introduction; Nuclear Receptors; Involvement in Hepatic Diseases; Stap/Ctyoglobin Expression In HSCS; Development (Ontogeny & Phylogeny); Ageing; Immunity & HSCS; Conclusions; Index.
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