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Title: |
Sperm Nuclear Maturation |
| Sub-title: |
A Basic & Clinical Approach |
Search Result:
| By (author): |
Ali Reza Talebi |
| ISBN10-13: |
1616681942 : 9781616681944 |
| Format: |
Paperback |
| Size: |
155x230mm |
| Pages: |
129 |
| Weight: |
.224 Kg. |
| Published: |
Nova Science Publishers, Inc (US) - October 2011 |
| List Price: |
52.99 Pounds Sterling |
| Availability: |
Temporarily Out of Stock, more expected soon
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| Subjects: |
DNA & Genome |
| In somatic cells, DNA is normally wrapped around the histones octamer to forms nucleosomes that eventually give rise to a solenoid DNA structure. Unlike somatic cells, in mammalian sperm, the development of spermatids into mature spermatozoa is accomplished by a series of structural and chemical modifications including a gradual replacement of lysine-rich histones by transition proteins and then by protamines which bind more tightly to DNA than histones, which results in compaction of chromatin in the sperm nucleus, a process which is termed 'sperm chromatin condensation'. This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa. |
| Table of Contents: |
| Preface; Part I. Mechanism of Sperm Nuclear Remodeling; Part II. The Origin of Sperm Chromatin/DNA Damages; Part III. Factors Affecting Sperm Chromatin & DNA Structure; Part IV. Sperm Chromatin/DNA Anomalies & Fertility; Index. |
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