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Title: Small Stress Proteins & Human Diseases
Edited by: Stéphanie Simon, André-Patrick Arrigo
ISBN10-13: 1614706360 : 9781614706366
Format: Paperback
Size: 155x230mm
Pages: 0
Weight: .982 Kg.
Published: Nova Science Publishers, Inc (US) - April   2012
List Price: 123.99 Pounds Sterling
Availability: Temporarily Out of Stock, more expected soon 
Subjects: Proteins
Essential for the defence against all kinds of stress, small stress proteins also play major roles in the physiology, development and differentiation of human cells. In spite of their beneficial roles, small stress proteins can also be deleterious for the organism, notably in some cancer pathologies where they can, through their anti-apoptotic properties, favour tumour development and interfere with the cytotoxic activity of anti-cancer drugs. This book proposes a focus on the recent knowledge in the field of the expression and putative role of small stress proteins in human health and diseases.
Table of Contents:
Preface; Cytoprotective Function of Small Stress Proteins to Fight Protein Conformational Diseases; Functional Symbiosis Between the Intermediate Filament Cytoskeleton & Small Heat Shock Proteins; The Two Lens Structure Proteins, Aa-Crystallin (Hspb4) & Ab-Crystallin (Hspb5), Control Apoptosis Through; Small Stress Proteins in the Central Nervous System: From Neurodegeneration To Neuroprotection.
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