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Title: |
Research Progress in Cancer Prevention |
Search Result:
| Edited by: |
Camille I Richard, Sarah E Mercier |
| ISBN10-13: |
1604567651 : 9781604567656 |
| Illustrations: |
tables & b/w photos |
| Format: |
Hardback |
| Size: |
180x260mm |
| Pages: |
277 |
| Weight: |
.776 Kg. |
| Published: |
Nova Science Publishers, Inc (US) - April 2009 |
| List Price: |
84.99 Pounds Sterling |
| Availability: |
Temporarily Out of Stock, more expected soon
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| Subjects: |
Oncology |
| Cancer has a complex aetiology, probably due to a sophisticated interaction between the genetic endowment of individuals and environmental risk factors. The continuing magnitude and severity of cancer as a major health problem renders cancer prevention an important area in the field of cancer research. Developments in cancer prevention have benefited from the recent advances in molecular and cellular biology. Several specific molecules have been identified as promising targets for cancer prevention and numerous agents have been synthesised, developed and tested to modulate the functions of these molecules. Given the ongoing advances in our understanding in the genesis of cancer, it is possible to develop new and better agents on a more mechanistic basis. The most striking examples for this mechanism-based approach for cancer prevention include: the role of inducible cyclooxygenase-2 (COX-2) in colon cancer and the preventive effects of COX-2 inhibitors (e.g., celecoxib); the involvement of oestrogen receptors in breast cancer and the development of selective estrogen receptor modulators (e.g., tamoxifen and raloxifene) for the prevention of this malignancy; and the function of androgen in prostate cancer and the use of 5-á-reductase inhibitors (e.g., finasteride) as a preventive measure. This book provides leading edge research from around the globe on this field. |
| Table of Contents: |
| Preface; Stimulation of DNA Base Excision Repair in Cancer Prevention; Dietary Compounds that Enhance DNA Repair & their Relevance to Cancer & Ageing; Environmental Tobacco Smoke Exposure & Respiratory Disease; Gender Differences in Lung Cancer; Using Intervention Mapping in Program Development to Promote Cervical Cancer Screening Among Chinese Women: From Needs Assessment, Intervention Development, to Program Evaluation; Preventing Cervical Cancer World-wide; Malignancies in Systemic Lupus Erythematosus & Other Immunosuppressed States; Associations & Etiologic Mechanisms; Cancers in Persons with Intellectual Disability: Current Data; Index. |
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