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Title: Research Developments in Stem Cells
By (author): Wade T Ereland
ISBN10-13: 1604564555 : 9781604564556
Format: Hardback
Pages: 0
Weight: .700 Kg.
Published: Nova Science Publishers, Inc (US) - July   2013
List Price: 114.99 Pounds Sterling
Availability: Pending Available 
Subjects: Cellular biology (cytology)
Stem cells are primal cells common to all multi-cellular organisms that retain the ability to renew them selves through cell division and can differentiate into a wide range of specialised cell types. The two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells. As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents the latest research in this dynamic field.
Table of Contents:
Preface; Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells to Repair Degenerative Intervertebral Discs; Differential Effects of Tri-Iodothyronine and Transforming Growth Factor-Beta 1 on Collagens Newly Synthesised by Human and Murine; Stem Cell-Based Therapies: The Roadmap to the Clinic; Derivation of Human Embryonic Stem Cell Lines; Commercialisation of Human Stem Cells and Stem Cell-Based Products: Real Dangers or Unnecessary Fears? European Perspective; Functional and Molecular Characterization of SP Cell Population Isolated from Mouse Primary Myoblast Culture; The Expression of Potential Markers of Nucleus Pulposus Phenotypes in Human Mesenchymal Stem Cells From Osteoarthritis Patients on Novel Nitrogen-Rich Plasma Polymer Surfaces; Effect of the N-terminal Peptide of Link Protein on Human Mesenchymal Stem Cells from Osteoarthritis Patients; Criteria for Patentability and Patent Scope in Europe: The Case of Human Stem Cells; The Ethics of Human Embryos and Embryonic Stem Cell Research; Index.
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