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Title: Advances in Medicine and Biology
Sub-title: Volume 174
Edited by: Leon V. Berhardt
ISBN10-13: 1536189219 : 9781536189216
Format: Hardback
Size: 230x155mm
Pages: 265
Weight: .518 Kg.
Published: Nova Science Publishers, Inc - December   2020
List Price: 221.99 Pounds Sterling
Availability: In Stock   Qty Available: 1
Subjects: Medicine: general issues
Volume 174 first provides a systematic review of the synthetic route and biological activities associated with 1,2,4-oxadiazole, 1,2,5-oxadiazole and 1,3,4-oxadiazole derivatives. The authors discuss recent advances in understanding the enantioselective separation and biological activities of the naturally occurring chiral compounds of essential oils. Subsequently, orthobiologics are discussed in the context of their potential in the management of early osteoarthritis, particularly focusing on the treatment of cartilage injuries. Another study aims to improve our understanding of the pathological mechanisms of choroidal neovascularization and approaches how to address the issue in central serous chorioretinopathy. An overview of the lignocellulolytic enzymes secreted by A. fumigatus during biomass conversion is provided, focusing on the quantitative expression of cellulolytic, hemicellulolytic, and ligninolytic enzymes and their synergetic mechanism during biomass degradation. The closing report reviews the current literature on metabolic syndrome, exploring the mechanisms proposed to better understand the role of environmental, genetic, and epigenetic aspects in the pathogenesis of this condition.
Table of Contents:
Preface; Biological Activity Spectrum of Oxadiazoles as a Privileged Scaffold in Medicinal Chemistry; Chiral Synthons from Essential Oils: Enantioselective Separation, Biological Activities and as Chiral Pools for the Synthesis of Natural Products; Orthobiologics to Treat Cartilage Injuries and Early Osteoarthritis in the Hip and Knee; Choroidal Neovascularization Secondary to Central Serous Chorioretinopathy: Understanding the Pathogenesis and Treatment Approaches; Aspergillus fumigatus: An Overview of Secretome in the Presence of Biomass; Role of the Environmental, Genetic and Epigenetic Aspects of the Metabolic Syndrome: A Comprehensive Approach; Index.
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